| cocaine; λ-cocaine | |
| Links: | 🌍 Wikipedia, 📏 NIST, 📖 PubMed, 📖Houben-Weyl, 2. Band (Cocain); p. 515, 519, 529, |
| MeSH: | Anesthetics; Anesthetics, Local; Central Nervous System Agents; Neurotransmitter Agents; Sensory System Agents; Vasoconstrictor Agents |
| CAS RN: | [50-36-2] |
| Formula: | C17H21NO4; 303.36 g/mol |
| InChiKey: | ZPUCINDJVBIVPJ-PFSRBDOWSA-N |
| SMILES: | COC(=O)[C@H]1[C@H](CC2CCC1N2C)OC(=O)c3ccccc3 |
| Pharmaceutical use: | anesthetic; bactericide |
| Toxicology (LD50): | 15.0 mg/Kg (cat, iv); 30.0 mg/Kg(cat, sc); 34.0 mg/Kg(dog, sc); 660 mg/Kg(frog, sc); 61.0 mg/Kg(guinea~pig, ip); 21.0 mg/Kg(guinea~pig, iv); 51.0 mg/Kg(guinea~pig, sc); 31.0 mg/Kg(mouse, iv); 101.0 mg/Kg(mouse, sc); 150 mg/Kg(mouse, sc); 189 mg/Kg(mouse, sc); 16.0 mg/Kg(rabbit, iv); 126 mg/Kg(rabbit, sc); 71.0 mg/Kg(rat, ip); 13.0 mg/Kg(rat, iv); 16.0 mg/Kg(rat, iv); 250 mg/Kg(rat, sc) |
| Dielectric constant: | 3.10 |
| Melting point: | 94 °C |
| August equation P(Torr) vs T(°C) | |
| Log10 partition octanol / water: | 2.30 |
| 1g dissolves in: 1.00g benzene; 1.32g aniline; 1.69g ethyl acetate; 1.79g piperidine; 2.78g diethylamine; 3.13g tetrachloromethane; 8.62g diethyl ether; 42.19g hexane; 714.29g water | |