| colchicine | |
| Links: | 🌍 Wikipedia, 📏 NIST, 📖 PubMed |
| MeSH: | Gout Suppressants; Mitosis Modulators; Tubulin Modulators |
| CAS RN: | [64-86-8] |
| Formula: | C22H25NO6; 399.44 g/mol |
| InChiKey: | IAKHMKGGTNLKSZ-INIZCTEOSA-N |
| SMILES: | COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O |
| Pharmaceutical use: | antiarthritic; anticancer; antiinflammatory; gout |
| Toxicology (LD50): | 3.000 mg/Kg (cat, iv); 3.000 mg/Kg(cat, or); 3.000 mg/Kg(cat, sc); 5.00000 mg/Kg(chicken, sc); 3.000 mg/Kg(dog, or); 3.000 mg/Kg(dog, sc); 3.00 mg/Kg(frog, sc); 21.0 mg/Kg(frog, sc); 67.0 mg/Kg(mouse, or); 7.00 mg/Kg(rabbit, iv); 5.00 mg/Kg(rabbit, sc); 3.00 mg/Kg(rat, iv); 6.00 mg/Kg(rat, sc) |
| Melting point: | 156 °C |
| Log10 partition octanol / water: | 1.30 |
| 1g dissolves in: 10.42g water; 74.63g ethyl acetate; 106.38g benzene; 769.23g diethyl ether; 833.33g tetrachloromethane; 1,666.67g hexane | |